9 Issues To Consider Before Using Progesterone Cream To Get Pregnant

9 Issues to consider before using progesterone cream to get pregnant:

I know you would agree with me when I tell you how difficult it is to conceive when contradictory information about using progesterone cream to get pregnant can be misleading.

The problem is that for years education on female hormones was limited at best.

Not only that but stress combined with toxins and pollution wreak havoc on our hormones.  All of this combined tricks the body into thinking there is too much estrogen to conceive.

Furthermore, some of the foods we eat can mimic estrogen also confusing the body. All of this combined causes hormonal imbalances.

I have helped many women combat hormonal balance issues. Our clinic has helped hundreds of women work through hormonal balance issues, perimenopause, menopause, thyroid issues, and hysterectomies, etc.

We have helped turn once desperate and frustrated women into happy, loving, productive, sexually active, stress-free women and more.

In this post, I am going to teach you all about and how to use progesterone cream to get pregnant, its role in conceiving, how to use it, and what to avoid.

#1: How progesterone helps you get pregnant

Using progesterone hormone therapy has a long history of helping women become pregnant.

Before 1993 women’s biology with regards to getting pregnant was still a mystery, the same year the pioneer of women’s hormonal replacement Dr. John R Lee wrote his first book entitled, Natural Progesterone: The Multiple Roles of a Remarkable Hormone, in an attempt to explain to his colleagues everything he had learned about progesterone and women’s hormonal balance.

Without any advertising, the book became a publishing success. In spite of its technical medical language, word spread and thousands of women, looking for the answers they haven’t been able to get anywhere else, bought it.

Hormone balance

We all know that balance is the key to a happy life and sustainable relationships, but it’s also the key to becoming pregnant.  During your menstrual cycle, many hormones play a part in ovulation and menstruation.

Progesterone is one of the major hormones involved in this process.  After you ovulate, progesterone production begins ramping up due to the luteinizing hormone that stimulates the remaining egg sac in the ovary to produce progesterone.

Progesterone is responsible for protecting the egg after fertilization and helps with the developing embryo.

If you become pregnant, more progesterone produced from the corpus luteum (egg sac) works overtime until about week 7.  Progesterone, therefore, is produced by the placenta for the duration of your pregnancy.

If for some reason you don’t get pregnant then your menstruation starts 14 days after ovulation.  When this happens, the corpus luteum disintegrates, causing levels of progesterone to drop and this is when the tissue breaks down and sheds.  This is what causes your period.

If you don’t have enough progesterone in the body, you can supplement with progesterone cream to get pregnant.

What progesterone does during pregnancy:

  • Progesterone protects and maintains the lining of the uterus protecting the fertilized egg
  • Make sure the embryo can survive
  • Prevents the rejection of the developing baby
  • Allows for the full development of the fetus
  • Helps the body use fat for energy
  • Prevents secondary sexual growth
  • Increases the libido
  • Activates osteoblasts to enhance new bone formation
  • Protects against cancers such as endometrial, breast, ovarian and prostate cancer

#2: Low progesterone vs. high progesterone

Estrogen Dominance – too much estrogen in the body

Progesterone deficiency happens for many reasons however the main reason is that estrogen dominance caused by too much estrogen, and therefore, there is not enough progesterone to balance the system.

You can supplement with progesterone cream to get pregnant which balances estrogen and reduces symptoms of estrogen dominance.

Some common reasons for estrogen dominance are:

  1. Eating commercially raised meats and dairy that contain large amounts of estrogens.
  2. When pollution and stress cause the body to think there more estrogen
  3. Consuming large amounts of soy can also mimic estrogen
  4. PCOS and endometriosis can also produce estrogen

Symptoms of estrogen dominance

Progesterone deficiency

Many signs show up in the body if you do not have enough progesterone during the correct times of your cycle, which is commonly called progesterone deficiency.

progesterone deficiency image

#3: Hormone testing

It’s always a good idea to consult your medical provider for testing options before starting any hormone therapy treatment.  

There are several types of testing options available from charting your menstrual cycle to determine the length of your luteal phase, to basal body temperature tracking your luteal, to saliva or blood tests.  

You can get blood, and saliva testing from your doctor or naturopathic doctor and even get saliva testing kits online.

BBT Charting

You can check your basal body temperature regularly and then chart your results. This can help determine the available progesterone during the luteal phase.  

There is a slight, steady rise in temperature after each ovulation where progesterone has increased. An irregular or consistently low ‘basal body temperature’ may indicate low progesterone which could mean luteal phase defect.

Length of the luteal phase

If you are using charting or ovulation detector strips, you may determine the length of your luteal phase.  If the date of ovulation is fewer than 11 days, this might mean that there are luteal phase defects.

Saliva Hormone Testing

Dr. Lee suggests that testing for hormones and progesterone should be done through saliva only.  Dr. Lee also mentions in many of his books that saliva is more accurate. However, most doctors will test serum (blood).  

It’s easy to use an in-home saliva test kit ordered online. With this, you can take the test during certain times of your menstrual cycle and mail it back for analysis.  Once the results are in you will either be able to access the results online, or get them mailed back to you.

Blood Hormone Testing

Even though Dr. Lee recommends the saliva test, it may be more convenient and appropriate to seek advice from your medical provider.  

Even if she prefers blood serum tests, you can get more options, or she can order an entire blood panel and check for other things during the visit.  Also, your doctor will be able to explain the results to you more thoroughly.

When to get your progesterone levels tested

You will want to test the peak progesterone levels.  To do this, you will test mid-luteal phase (either seven days after ovulation, or 7 days before expected menses).

However, this day will vary according to each woman’s cycle length. For example, for a 28-day cycle, day 21 progesterone testing is what is required, but for a 35-day cycle, progesterone is ideally measured around day 28.

#4: How to use progesterone cream to get pregnant

The most efficient way to take progesterone is to use progesterone cream to get pregnant.  Creams, known as topical’s or transdermal’s absorbed through the skin bypassing the liver.

Progesterone absorbed through the skin into the underlying fat helps slowly dissolve the progesterone into the bloodstream.  

By using progesterone cream in this way, it acts as a ‘time released’ application. To match the body’s progesterone cycle, progesterone cream should be applied twice per day, morning and night.

#5: Suggested uses for progesterone cream for fertility

Progesterone cream can easily be absorbed in the skin in a matter of seconds.  Therefore, you can use skin cream anywhere as long as you rotate the application every other day.  

It’s best to follow a skin rotation application where you use four different parts of your body and rotate each day, starting over on the 4th day.

The best areas for application are:

  • Face
  • Neck
  • Upper Chest
  • Breasts
  • Inner arms
  • Palms of hands and feet

#6: How to apply progesterone cream to get pregnant

More is not always better, in fact, too much progesterone can cause hormonal imbalances that may mimic too much estrogen side effects. General dosage is around 40 mg daily taken in two dosages of 20 mg daily, usually in the morning and evenings.  

Progesterone should be used directly after ovulation around 14 days in the menstrual cycle and stop using progesterone once you start your period.

#7: Ovulation

As mentioned before you might want to track your ovulation with a fertilization chart.  

One of the best ways is to detect ovulation is to use OPK (ovulation predictor strips) test strips, an ovulation microscope and BBT basal body temperature charting.  

Then once ovulation is detected, you can begin progesterone cream to get pregnant right away.

#8: Loading doses

Dr. Lee recommends loading dosing which requires a higher dose of progesterone cream to get pregnant.  

He recommends following a loading dose protocol for the first 1-2 months of progesterone cream use. What this does is to help replenish progesterone stored in the body fat.  

After 2-3 months of the loading, the dose can be lowered to normal use. The loading dose is used for women who have had many years or months of no ovulation cycles called an-ovulation.  

An-ovulation can be sometimes referred to as infertility but not always the case. What this does is create a progesterone deficiency.

As each cycle that passes without ovulation estrogen dominance can increase, also very thin women with little body fat can become estrogen dominant causing hormone imbalances that may contribute to infertility.

  1. Loading dose – this is twice the regular dose: Use 40mg twice a day, one 40mg application in the morning and one 40 mg application at night, for a total of 80 mg’s of progesterone cream to get pregnant per day. Apply for two weeks before your period (about day 14 in the cycle), up until menstruation begins.
  2. Regular dose this is half the loading dose: Use 20mg twice a day, one 20mg application in the morning and one 20 mg application at night, for a total of 40 mg’s of natural progesterone cream a day. Apply for two weeks before your period (about day 14 in the cycle), up until menstruation begins.
  3. Inducing ovulation using progesterone: Dr. Lee had successful results with patients using this dosing regimen who were able to get pregnant using progesterone cream loading.  There were quite a few patients who were not ovulating and were still able to conceive. For two to four months he had them use natural progesterone from days 5 to 26 in the cycle (stopping on day 26 to bring on menstruation).

NOTE: Using the progesterone cream to get pregnant before ovulation effectively suppressed ovulation.  

After using this loading dose regimen for a few months, he then had them discontinue progesterone use entirely.  

If a woman who chose this route had follicles left, they responded favorably to this form of treatment.

#9: Preventing miscarriage and progesterone

It’s possible that low progesterone is the cause of many miscarriages.  

Since progesterone is not only responsible for taking care of the womb by maintaining uterine lining, it also aids in reducing blood clots. Furthermore, it aids in supporting the fetus’s immune system and is one of the main hormones involved in a healthy pregnancy.  

Supplementing with progesterone cream to get pregnant may be the choice that you come to after consulting your doctor.

Always consult your medical provider or doctor especially if you feel this may be the issue you are having regarding your pregnancy.   

Its advisable to get your hormone levels checked regularly to ensure everything is in good working order.

Make sure to have at least two jars of progesterone cream to get pregnant on hand, because running out could cause a significant drop in progesterone which may cause the menstrual cycle to begin.


As you can see supplementing with progesterone cream to get pregnant could be the vital step that is needed to support and protect your womb and carry your baby healthy to term.

Remember if you do become pregnant contact your medical provider so they can monitor your progesterone levels and see that you are taking the necessary steps for a healthy pregnancy.

Tune in for actionable advice on topics like bioidentical progesterone cream, micronized progesterone, wild yam progesterone cream, and progesterone dominance tips and symptoms.

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1. Lee, John, M.D. (2006) Hormone Balance Made Simple. Werner Books: New York, New York.
2. Lee, John, M.D. (1999). What Your Doctor May Not Tell You About Premenopause. Grand Central Life & Style – Hachette Book Group: New York, New York.


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